Data & ReproProtein Structure & DesignFreedomIntelligence/OpenClaw-Medical-SkillsData & Reproduction
BI

bindcraft

Maintainer FreedomIntelligence · Last updated April 1, 2026

End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate. For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc.….

OpenClawNanoClawAnalysisReproductionbindcraft🔬 omics & computational biologyprotein structure & designend

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bindcraft

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • First time? See Installation Guide to set up Modal and biomodals.

Source Doc

Excerpt From SKILL.md

Option 1: Modal (recommended)

GPU: L40S (48GB) | Timeout: 3600s default

Key parameters

ParameterDefaultRangeDescription
--target-pdbrequiredpathTarget structure
--target-chainrequiredA-ZTarget chain(s)
--binder-lengths70-10040-150Length range
--hotspotsNoneresiduesTarget hotspots
--num-designs501-500Number of designs
--protocoldefaultfast/default/slowQuality vs speed

Protocols

ProtocolSpeedQualityUse Case
fastFastLowerInitial screening
defaultMediumGoodStandard campaigns
slowSlowHighFinal production

Use cases

  • Use bindcraft in research workflows aligned with this subject area.
  • Follow the upstream documentation for the full working procedure.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

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