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bio-blast-searches

Maintainer FreedomIntelligence · Last updated April 1, 2026

Run BLAST searches against local or remote databases for sequence homology.

OpenClawNanoClawDiscoveryDataset Buildingbio-blast-searches🧠 bioos extended suitebioos extended bioinformatics suiterun

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-blast-searches

Maintainer: FreedomIntelligence
License: MIT
Last updated: April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

Run BLAST searches against NCBI databases using Biopython's Bio.Blast module.
result_handle = NCBIWWW.qblast('blastn', 'nt', sequence).

Source Doc

Excerpt From SKILL.md

BLAST Programs

Program	Query	Database	Use Case
`blastn`	Nucleotide	Nucleotide	DNA/RNA sequence similarity
`blastp`	Protein	Protein	Protein sequence similarity
`blastx`	Nucleotide	Protein	Find protein hits for DNA query
`tblastn`	Protein	Nucleotide	Find DNA encoding protein-like
`tblastx`	Nucleotide	Nucleotide	Translated vs translated

NCBIWWW.qblast()

Submit a BLAST query to NCBI servers.

from Bio.Blast import NCBIWWW

## Common Databases

**Nucleotide:**
| Database | Description |
|----------|-------------|
| `nt` | All GenBank + EMBL + DDBJ |
| `refseq_rna` | RefSeq RNA sequences |
| `refseq_genomic` | RefSeq genomic sequences |

**Protein:**
| Database | Description |
|----------|-------------|
| `nr` | Non-redundant protein |
| `refseq_protein` | RefSeq proteins |
| `swissprot` | SwissProt (curated) |
| `pdb` | Protein structures |