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bio-comparative-genomics-positive-selection

Maintainer FreedomIntelligence · Last updated April 1, 2026

Test for positive selection with PAML, HyPhy, or dN/dS ratios.

OpenClawNanoClawAnalysisReproductionbio-comparative-genomics-positive-selection🧠 bioos extended suitebioos extended bioinformatics suitetest

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-comparative-genomics-positive-selection

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • ω < 1: Purifying (negative) selection - deleterious mutations removed.
  • ω = 1: Neutral evolution - no selective pressure.
  • ω > 1: Positive (diversifying) selection - advantageous mutations favored.
  • CDS sequences (in-frame, no stop codons except terminal).
  • Multiple sequence alignment already performed.

Use cases

  • Use bio-comparative-genomics-positive-selection for genomics and bioinformatics workflows.
  • Apply bio-comparative-genomics-positive-selection to sequencing, variant, or omics analysis tasks.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

Upstream Related Skills

  • comparative-genomics/synteny-analysis - Find syntenic genes for selection tests
  • comparative-genomics/ortholog-inference - Identify orthologs for analysis
  • alignment/msa-parsing - Parse and manipulate codon alignments
  • phylogenetics/modern-tree-inference - Generate trees for codeml

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