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Maintainer FreedomIntelligence · Last updated April 1, 2026
Filter and select sequences by criteria (length, ID, GC content, patterns) using Biopython. Use when subsetting sequences, removing unwanted records, or selecting by specific criteria.
Original source
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-filter-sequences
Skill Snapshot
Source Doc
Use generator expressions for memory-efficient filtering:
Goal: Extract sequences whose IDs appear in an external list file.
Approach: Load IDs into a set for O(1) lookup, then stream-filter and write matches.
Reference (BioPython 1.83+):
Goal: Remove sequences that fail any of several quality/content thresholds.
Approach: Define a predicate function that checks all criteria, apply it as a generator filter, and write survivors.
Reference (BioPython 1.83+):
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