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BI

bio-local-blast

Maintainer FreedomIntelligence · Last updated April 1, 2026

Set up and run BLAST+ locally with custom databases.

OpenClawNanoClawDiscoveryDataset Buildingbio-local-blast🧠 bioos extended suitebioos extended bioinformatics suiteset

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-local-blast

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • Run BLAST searches locally using NCBI BLAST+ command-line tools.
  • sudo apt install ncbi-blast+.

Source Doc

Excerpt From SKILL.md

BLAST+ Programs

CommandQueryDatabaseDescription
blastnDNADNANucleotide-nucleotide
blastpProteinProteinProtein-protein
blastxDNAProteinTranslated query vs protein
tblastnProteinDNAProtein vs translated DB
tblastxDNADNATranslated vs translated
makeblastdb--Create BLAST database

Create nucleotide database

makeblastdb -in sequences.fasta -dbtype nucl -out my_db

Create protein database

makeblastdb -in proteins.fasta -dbtype prot -out my_proteins

Use cases

  • Use bio-local-blast in research workflows aligned with this subject area.
  • Follow the upstream documentation for the full working procedure.

Not for

  • Do not assume this entry replaces the original database documentation or API notes.

Upstream Related Skills

  • blast-searches - Remote BLAST via NCBI (no installation needed)
  • sequence-io - Read/write FASTA files for queries
  • batch-downloads - Download sequences to build local databases

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