Data & ReproClinical MedicineFreedomIntelligence/OpenClaw-Medical-SkillsData & Reproduction
BI

bio-longitudinal-monitoring

Maintainer FreedomIntelligence · Last updated April 1, 2026

Tracks ctDNA dynamics over time for treatment response monitoring using serial liquid biopsy samples. Analyzes tumor fraction trends, mutation clearance kinetics, and defines molecular response criteria. Use when monitoring patients during therapy or detecting molecular relapse before clinical progression.

OpenClawNanoClawAnalysisReproductionbio-longitudinal-monitoring🧬 bioinformatics (gptomics bio-* suite)bioinformatics — clinical databases & variant analysistracks

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-longitudinal-monitoring

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • Python: pandas + matplotlib for trend analysis and molecular response classification.
  • Track ctDNA levels over my patient's treatment" → Monitor tumor fraction and mutation dynamics across serial liquid biopsy timepoints for treatment response assessment and early relapse detection. Python: pandas + matplotlib for trend analysis and molecular response classification.
  • Track ctDNA dynamics over treatment for response assessment and relapse detection.

Source Doc

Excerpt From SKILL.md

Clinical Integration

Goal: Generate a structured monitoring report combining tumor fraction dynamics, mutation clearance status, and molecular response classification for clinical decision support.

Approach: Aggregate tumor fraction trend analysis, mutation tracking pivot tables, and response criteria into a single report dictionary with standardized molecular response categories.

Use cases

  • Use when monitoring patients during therapy or detecting molecular relapse before clinical progression.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

Upstream Related Skills

  • ctdna-mutation-detection - Detect mutations to track
  • tumor-fraction-estimation - Estimate tumor fraction per timepoint
  • fragment-analysis - Complement with fragmentomics trends

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