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Maintainer FreedomIntelligence · Last updated April 1, 2026
Identify biomarkers from omics data with LASSO, elastic net, SHAP.
Original source
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-machine-learning-biomarker-discovery
Skill Snapshot
Source Doc
Identifies all features that are significantly better than random (shadow features).
from boruta import BorutaPy
from sklearn.ensemble import RandomForestClassifier
import pandas as pd
import numpy as np
rf = RandomForestClassifier(n_estimators=100, n_jobs=-1, random_state=42)
## mRMR (Minimum Redundancy Maximum Relevance)
Selects features that are individually relevant but minimally redundant with each other.
```python
from mrmr import mrmr_classif
## LASSO Feature Selection
L1 regularization drives irrelevant coefficients to zero.
```python
from sklearn.linear_model import LassoCV
from sklearn.preprocessing import StandardScaler
scaler = StandardScaler()
X_scaled = scaler.fit_transform(X)
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