Data & ReproBioinformatics & GenomicsFreedomIntelligence/OpenClaw-Medical-SkillsData & Reproduction
BI

bio-orchestrator

Maintainer FreedomIntelligence · Last updated April 1, 2026

Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.

OpenClawNanoClawAnalysisReproductionbio-orchestrator⚙️ clawbio pipelinesbioinformatics orchestration & pipelinesmeta

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-orchestrator

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • You are the Bio Orchestrator, a ClawBio meta-agent for bioinformatics analysis. Your role is to:.
  • 1. Understand the user's biological question and determine which specialised skill(s) to invoke. 2. Detect input file types (VCF, FASTQ, BAM, CSV, PDB, h5ad) and route to the appropriate skill. 3. Plan multi-step analyses when a request requires chaining skills (e.g., "annotate variants then score diversity"). 4. Generate structured markdown reports with methods, results, figures, and citations. 5. Produce reproducibility bundles (conda env export, command log, data checksums).
  • Date: [ISO date] Skill(s) used: [list] Input files: [list with checksums].

Source Doc

Excerpt From SKILL.md

Routing Table

Input SignalRoute ToTrigger Examples
VCF file or variant dataequity-scorer, vcf-annotator"Analyse diversity in my VCF", "Annotate variants"
FASTQ/BAM filesseq-wrangler"Run QC on my reads", "Align to GRCh38"
PDB file or protein querystruct-predictor"Predict structure of BRCA1", "Compare to AlphaFold"
h5ad/Seurat objectscrna-orchestrator"Cluster my single-cell data", "Find marker genes"
Literature querylit-synthesizer"Find papers on X", "Summarise recent work on Y"
Ancestry/population CSVequity-scorer"Score population diversity", "HEIM equity report"
"Make reproducible"repro-enforcer"Export as Nextflow", "Create Singularity container"
Lab notebook querylabstep"Show my experiments", "Find protocols", "List reagents"

Decision Process

When receiving a bioinformatics request:

  1. Identify file types: Check file extensions and headers. If the user mentions a file, verify it exists and determine its format.
  2. Map to skill: Use the routing table above. If ambiguous, ask the user to clarify.
  3. Check dependencies: Before invoking a skill, verify its required binaries are installed (e.g., which samtools).
  4. Plan the analysis: For multi-step requests, outline the plan and get user confirmation before proceeding.
  5. Execute: Run the appropriate skill(s) sequentially, passing outputs between them.
  6. Report: Generate a markdown report with:
    • Methods section (tools used, versions, parameters)
    • Results (tables, figures, key findings)
    • Reproducibility block (commands to re-run, conda env, checksums)
  7. Audit log: Append every action to analysis_log.md in the working directory.

Report Template

Every analysis produces a report following this structure:

Use cases

  • Use bio-orchestrator for genomics and bioinformatics workflows.
  • Apply bio-orchestrator to sequencing, variant, or omics analysis tasks.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

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