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bio-population-genetics-association-testing

Maintainer FreedomIntelligence · Last updated April 1, 2026

GWAS association testing with PLINK, BOLT-LMM, or SAIGE.

OpenClawNanoClawAnalysisReproductionbio-population-genetics-association-testing🧠 bioos extended suitebioos extended bioinformatics suitegwas

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-population-genetics-association-testing

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • GWAS analysis using PLINK 2.0's unified --glm command for case-control and quantitative traits.
  • plink2 --bfile data --glm --out results.

Source Doc

Excerpt From SKILL.md

With phenotype file

plink2 --bfile data --pheno pheno.txt --glm --out results


## Linear regression for quantitative traits

plink2 --bfile data --pheno pheno.txt --glm --out results

Include covariates (sex, age, PCs)

plink2 --bfile data
--pheno pheno.txt
--covar covariates.txt
--glm --out results

Use cases

  • Use bio-population-genetics-association-testing for genomics and bioinformatics workflows.
  • Apply bio-population-genetics-association-testing to sequencing, variant, or omics analysis tasks.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

Upstream Related Skills

  • plink-basics - Data preparation and QC
  • population-structure - PCA for stratification control
  • linkage-disequilibrium - LD pruning before analysis

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