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BI
bio-reverse-complement
Maintainer FreedomIntelligence · Last updated April 1, 2026
Compute reverse complement and strand-aware sequence operations.
Original source
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-reverse-complement
- Maintainer
- FreedomIntelligence
- License
- MIT
- Last updated
- April 1, 2026
Skill Snapshot
Key Details From SKILL.md
Key Notes
- Generate complementary and reverse complementary sequences using Biopython.
Source Doc
Excerpt From SKILL.md
reverse_complement()
Returns the reverse complement (5' to 3' of the opposite strand).
This is the most commonly used operation - it gives you the sequence of the opposite strand in the conventional 5' to 3' direction.
complement()
Returns the complement without reversing.
Less commonly used - gives the opposite strand but in 3' to 5' direction.
reverse_complement_rna()
For RNA sequences (uses U instead of T):
Use cases
- Use bio-reverse-complement for genomics and bioinformatics workflows.
- Apply bio-reverse-complement to sequencing, variant, or omics analysis tasks.
Not for
- Do not rely on this catalog entry alone for installation or maintenance details.
Upstream Related Skills
- seq-objects - Create Seq objects to complement
- transcription-translation - Six-frame translation uses reverse complement
- motif-search - Search both strands for motifs
- restriction-analysis/restriction-sites - Restriction sites are often palindromic
- alignment-files/sam-bam-basics - BAM FLAG indicates read strand; use samtools view -f 16 for reverse
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