Data & ReproProtein Structure & DesignFreedomIntelligence/OpenClaw-Medical-SkillsData & Reproduction
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bio-uniprot-access

Maintainer FreedomIntelligence · Last updated April 1, 2026

Query UniProt for protein sequences, annotations, and cross-references.

OpenClawNanoClawAnalysisReproductionbio-uniprot-access🧠 bioos extended suitebioos extended bioinformatics suitequery

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-uniprot-access

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • Query UniProt for protein sequences, functional annotations, and cross-references.
  • query = 'organism_id:9606 AND keyword:kinase AND database:pdb AND reviewed:true' results = search_uniprot(query, size=100).

Source Doc

Excerpt From SKILL.md

Query Syntax

QueryDescription
gene:TP53Gene name
organism_id:9606Human (NCBI taxonomy)
reviewed:trueSwiss-Prot only
length:[100 TO 500]Sequence length range
go:0006915GO term (apoptosis)
keyword:kinaseKeyword
ec:2.7.1.1Enzyme classification
database:pdbHas PDB structure

Stream Large Results

def search_all(query, format='tsv', fields=None):
    '''Stream all results for large queries'''
    url = 'https://rest.uniprot.org/uniprotkb/stream'
    params = {'query': query, 'format': format}
    if fields:
        params['fields'] = ','.join(fields)
    response = requests.get(url, params=params, stream=True)
    return response.text

## Get all human proteins as TSV

all_human = search_all('organism_id:9606 AND reviewed:true',
                       fields=['accession', 'gene_names', 'protein_name'])

Use cases

  • Use bio-uniprot-access in research workflows aligned with this subject area.
  • Follow the upstream documentation for the full working procedure.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

Upstream Related Skills

  • database-access/entrez-fetch - NCBI protein access
  • database-access/blast-searches - BLAST against UniProt
  • structural-biology/structure-io - Download PDB structures
  • structural-biology/alphafold-predictions - AlphaFold structures

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