Data & ReproProtein Structure & DesignFreedomIntelligence/OpenClaw-Medical-SkillsData & Reproduction
BO

boltzgen

Maintainer FreedomIntelligence · Last updated April 1, 2026

All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use….

OpenClawNanoClawAnalysisReproductionboltzgen🔬 omics & computational biologyprotein structure & designall

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/boltzgen

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • git clone https://github.com/hgbrian/biomodals && cd biomodals.
  • modal run modal_boltzgen.py \ --input-yaml binder_config.yaml \ --protocol protein-anything \ --num-designs 50.

Source Doc

Excerpt From SKILL.md

Prerequisites

RequirementMinimumRecommended
Python3.10+3.11
CUDA12.0+12.1+
GPU VRAM24GB48GB (L40S)
RAM32GB64GB

How to run

First time? See Installation Guide to set up Modal and biomodals.

With custom GPU

GPU=L40S modal run modal_boltzgen.py
--input-yaml binder_config.yaml
--protocol protein-anything
--num-designs 100


**GPU**: L40S (48GB) recommended | **Timeout**: 120min default

**Available protocols**: `protein-anything`, `peptide-anything`, `protein-small_molecule`, `nanobody-anything`, `antibody-anything`

Use cases

  • Use boltzgen in research workflows aligned with this subject area.
  • Follow the upstream documentation for the full working procedure.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

Related skills

Related skills

Back to directory
AD
Data & ReproProtein Structure & Design

Adaptyv

Adaptyv is a cloud laboratory platform that provides automated protein testing and validation services. Submit protein sequences via API or…

Claude CodeOpenClawAnalysis
K-Dense-AI/claude-scientific-skillsView
AL
Data & ReproProtein Structure & Design

alphafold

Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) P…

OpenClawNanoClawAnalysis
FreedomIntelligence/OpenClaw-Medical-SkillsView
AL
Data & ReproProtein Structure & Design

AlphaFold DB

AlphaFold DB is a public repository of AI-predicted 3D protein structures for over 200 million proteins, maintained by DeepMind and EMBL-EBI…

Claude CodeOpenClawAnalysis
K-Dense-AI/claude-scientific-skillsView
AN
Data & ReproProtein Structure & Design

antibody-design-agent

Antibody design: epitope mapping, CDR engineering, bispecific construction.

OpenClawNanoClawAnalysis
FreedomIntelligence/OpenClaw-Medical-SkillsView