Data & ReproProtein Structure & DesignFreedomIntelligence/OpenClaw-Medical-SkillsData & Reproduction
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foldseek

Maintainer FreedomIntelligence · Last updated April 1, 2026

Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity. For sequence similarity, use uniprot BLAST. For structure prediction, use chai or boltz.

OpenClawNanoClawAnalysisReproductionfoldseek🔬 omics & computational biologyprotein structure & designstructure

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/foldseek

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • curl -X POST "https://search.foldseek.com/api/ticket" \ -F "[email protected]" \ -F "database[]=afdb50" \ -F "database[]=pdb100".
  • conda install -c conda-forge -c bioconda foldseek.

Source Doc

Excerpt From SKILL.md

Prerequisites

RequirementMinimumRecommended
Python3.8+3.10
RAM8GB16GB
Disk10GB50GB (for local databases)

How to run

Note: Foldseek can run locally or via web server. No GPU required.

Search PDB

foldseek easy-search query.pdb /path/to/pdb100 results.m8 tmp/

Use cases

  • Use foldseek in research workflows aligned with this subject area.
  • Follow the upstream documentation for the full working procedure.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

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