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KR

kragen-knowledge-graph

Maintainer FreedomIntelligence · Last updated April 1, 2026

KRAGEN knowledge graph for biomedical entity relationships and reasoning.

OpenClawNanoClawAnalysisReproductionkragen-knowledge-graph🧠 bioos extended suiteresearch infrastructure & agentskragen

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/kragen-knowledge-graph

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • A knowledge graph-enhanced Retrieval-Augmented Generation system for biomedical problem solving, using Graph-of-Thoughts (GoT) reasoning.
  • Complex Reasoning: Questions requiring multi-hop deduction (e.g., "How does gene A influence disease B via protein C?").
  • Hypothesis Verification: Checking if a proposed mechanism is supported by existing knowledge graphs.
  • Literature Synthesis: Combining facts from structured DBs and unstructured text.
  • Complex Reasoning: Questions requiring multi-hop deduction (e.g., "How does gene A influence disease B via protein C?"). Hypothesis Verification: Checking if a proposed mechanism is supported by existing knowledge graphs. * Literature Synthesis: Combining facts from structured DBs and unstructured text.

Source Doc

Excerpt From SKILL.md

Core Capabilities

  1. Graph Retrieval: Query biomedical knowledge graphs (e.g., PrimeKG, SPOKE).
  2. Graph-of-Thoughts: structured reasoning over retrieved nodes.
  3. Vector DB Integration: Combines graph data with vector embeddings for hybrid search.

Workflow

  1. Input: Natural language question.
  2. Retrieval: Fetch relevant sub-graph and similar text chunks.
  3. Reasoning: LLM traverses the graph to find connecting paths.
  4. Answer: Generate response with citation of graph nodes.

Example Usage

User: "Explain the mechanism connecting BRCA1 mutations to ovarian cancer."

Agent Action:

Use cases

  • Use kragen-knowledge-graph in research workflows aligned with this subject area.
  • Follow the upstream documentation for the full working procedure.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

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