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pharmgx-reporter
Maintainer FreedomIntelligence · Last updated April 1, 2026
Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) — 12 genes, 31 SNPs, 51 drugs.
Original source
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/pharmgx-reporter
- Maintainer
- FreedomIntelligence
- License
- MIT
- Last updated
- April 1, 2026
Skill Snapshot
Key Details From SKILL.md
Key Notes
- You are PharmGx Reporter, a specialised ClawBio agent for pharmacogenomic analysis. Your role is to generate a personalised drug–gene interaction report from consumer genetic data.
- python skills/pharmgx-reporter/pharmgx_reporter.py \ --input <patient_file> --output <report_dir>.
Source Doc
Excerpt From SKILL.md
Why This Exists
- Without it: Users must manually cross-reference their raw genotype files against CPIC guidelines — a multi-hour process requiring genetics expertise
- With it: Upload a 23andMe or AncestryDNA file and get a structured report covering 12 genes and 51 drugs in seconds
- Why ClawBio: Grounded in CPIC guidelines and FDA-approved PGx biomarkers, not LLM guesswork. Every recommendation traces to a published star-allele → phenotype → drug mapping.
Core Capabilities
- Genotype Parsing: Auto-detects 23andMe or AncestryDNA format, extracts 31 pharmacogenomic SNPs
- Star Allele Calling: Maps diplotypes to metaboliser phenotypes (Poor, Intermediate, Normal, Rapid, Ultra-rapid)
- Drug Recommendation: Looks up CPIC-level drug guidance for 51 medications across 12 genes
- Single-Drug Mode:
--drugflag for quick lookup of one medication (used by Drug Photo skill)
Input Formats
| Format | Extension | Required Fields | Example |
|---|---|---|---|
| 23andMe raw data | .txt, .txt.gz | rsid, chromosome, position, genotype | demo_patient.txt |
| AncestryDNA raw data | .txt | rsid, chromosome, position, allele1, allele2 | — |
Use cases
- Use pharmgx-reporter for medicinal chemistry and drug-discovery work.
- Apply pharmgx-reporter to compound, target, or screening workflows.
Not for
- Do not rely on this catalog entry alone for installation or maintenance details.
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