Data & ReproSingle-Cell & Spatial OmicsFreedomIntelligence/OpenClaw-Medical-SkillsData & Reproduction
TC

tcga-bulk-data-preprocessing-with-omicverse

Maintainer FreedomIntelligence · Last updated April 1, 2026

Follow this skill to recreate the preprocessing routine from [`t_tcga.ipynb`](../../omicverse_guide/docs/Tutorials-bulk/t_tcga.ipynb). It automates loading TCGA downloads, generating raw/normalised matrices, initialising metadata, and running survival analyses through `ov.bulk.pyTCGA`.

OpenClawNanoClawAnalysisReproductiontcga-preprocessing🔬 omics & computational biologysingle-cell & spatial omicsguide

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/tcga-preprocessing

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • Follow this skill to recreate the preprocessing routine from t_tcga.ipynb. It automates loading TCGA downloads, generating raw/normalised matrices, initialising metadata, and running survival analyses through ov.bulk.pyTCGA.
  • Confirm the user has:.
  • gdc_sample_sheet.<date>.tsv from the TCGA Sample Sheet export.
  • The decompressed gdc_download_xxxxx directory containing expression archives.
  • The clinical.cart.<date> directory with clinical XML/JSON files.

Source Doc

Excerpt From SKILL.md

Examples

  • "Read my TCGA OV download, initialise metadata, and plot MYC survival curves using DESeq-normalised counts."
  • "Reload a saved AnnData file, attach survival annotations, and export the updated .h5ad."
  • "Run survival analysis for all genes and store the enriched dataset."

Use cases

  • Use tcga-bulk-data-preprocessing-with-omicverse for single-cell or spatial omics analysis.
  • Apply tcga-bulk-data-preprocessing-with-omicverse to clustering, integration, or trajectory workflows.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

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