Data & ReproProtein Structure & DesignFreedomIntelligence/OpenClaw-Medical-SkillsData & Reproduction
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tooluniverse-infectious-disease

Maintainer FreedomIntelligence · Last updated April 1, 2026

Rapid pathogen characterization and drug repurposing analysis for infectious disease outbreaks. Identifies pathogen taxonomy, essential proteins, predicts structures, and screens existing drugs via docking. Use when facing novel pathogens, emerging infections, or needing rapid therapeutic options during outbreaks.

OpenClawNanoClawAnalysisReproductiontooluniverse-infectious-disease🏥 medical & clinicalmedical toolsrapid

Original source

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/tooluniverse-infectious-disease

Maintainer
FreedomIntelligence
License
MIT
Last updated
April 1, 2026

Skill Snapshot

Key Details From SKILL.md

2 min

Key Notes

  • Rapid response system for emerging pathogens using taxonomy analysis, target identification, structure prediction, and computational drug repurposing.
  • KEY PRINCIPLES: 1. Speed is critical - Optimize for rapid actionable intelligence 2. Target essential proteins - Focus on conserved, essential viral/bacterial proteins 3. Leverage existing drugs - Prioritize FDA-approved compounds for repurposing 4. Structure-guided - Use NvidiaNIM for rapid structure prediction and docking 5. Evidence-graded - Grade repurposing candidates by evidence strength 6. Actionable output - Prioritized drug candidates with rationale 7. English-first queries - Always use English terms in tool calls (pathogen names, protein names, drug names), even if the user writes in another language. Only try original-language terms as a fallback. Respond in the user's language.

Source Doc

Excerpt From SKILL.md

When to Use

Apply when user asks:

  • "New pathogen detected - what drugs might work?"
  • "Emerging virus [X] - therapeutic options?"
  • "Drug repurposing candidates for [pathogen]"
  • "What do we know about [novel coronavirus/bacteria]?"
  • "Essential targets in [pathogen] for drug development"
  • "Can we repurpose [drug] against [pathogen]?"

1. Report-First Approach (MANDATORY)

  1. Create the report file FIRST:

    • File name: [PATHOGEN]_outbreak_intelligence.md
    • Initialize with section headers
    • Add placeholder: [Analyzing...]
  2. Progressively update as you gather data

  3. Output separate files:

    • [PATHOGEN]_drug_candidates.csv - Ranked repurposing candidates
    • [PATHOGEN]_target_proteins.csv - Druggable targets

Target: RNA-dependent RNA polymerase (RdRp)

  • UniProt: P0DTD1 (NSP12)
  • Essentiality: Required for replication
  • Conservation: >95% across variants
  • Drug precedent: Remdesivir targets RdRp

Source: UniProt via UniProt_search, literature review


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Use cases

  • Use when facing novel pathogens, emerging infections, or needing rapid therapeutic options during outbreaks.

Not for

  • Do not rely on this catalog entry alone for installation or maintenance details.

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