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TO
tooluniverse-precision-oncology
Maintainer FreedomIntelligence · Last updated April 1, 2026
Provide actionable treatment recommendations for cancer patients based on molecular profile. Interprets tumor mutations, identifies FDA-approved therapies, finds resistance mechanisms, matches clinical trials. Use when oncologist asks about treatment options for specific mutations (EGFR, KRAS, BRAF, etc.), therapy resistance, or clinical trial eligibility.
Original source
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/tooluniverse-precision-oncology
- Maintainer
- FreedomIntelligence
- License
- MIT
- Last updated
- April 1, 2026
Skill Snapshot
Key Details From SKILL.md
Key Notes
- Provide actionable treatment recommendations for cancer patients based on their molecular profile using CIViC, ClinVar, OpenTargets, ClinicalTrials.gov, and structure-based analysis.
- KEY PRINCIPLES: 1. Report-first - Create report file FIRST, update progressively 2. Evidence-graded - Every recommendation has evidence level 3. Actionable output - Prioritized treatment options, not data dumps 4. Clinical focus - Answer "what should we do?" not "what exists?" 5. English-first queries - Always use English terms in tool calls (mutations, drug names, cancer types), even if the user writes in another language. Only try original-language terms as a fallback. Respond in the user's language.
- Patient ID: [ID] | Date: [Date].
Source Doc
Excerpt From SKILL.md
When to Use
Apply when user asks:
- "Patient has [cancer] with [mutation] - what treatments?"
- "What are options for EGFR-mutant lung cancer?"
- "Patient failed [drug], what's next?"
- "Clinical trials for KRAS G12C?"
- "Why isn't [drug] working anymore?"
Phase 0: Tool Verification
CRITICAL: Verify tool parameters before first use.
| Tool | WRONG | CORRECT |
|---|---|---|
civic_get_variant | variant_name | id (numeric) |
civic_get_evidence_item | variant_id | id |
OpenTargets_* | ensemblID | ensemblId (camelCase) |
search_clinical_trials | disease | condition |
1.2 Validate Variant Nomenclature
- HGVS protein: p.L858R, p.V600E
- cDNA: c.2573T>G
- Common names: T790M, G12C
Use cases
- Use when oncologist asks about treatment options for specific mutations (EGFR, KRAS, BRAF, etc.
Not for
- Do not rely on this catalog entry alone for installation or maintenance details.
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