AD
Data & Repro
Adaptyv
Adaptyv is a cloud laboratory platform that provides automated protein testing and validation services. Submit protein sequences via API or…
K-Dense-AI/claude-scientific-skillsView
Data & Repro
PR
protein-interaction-network-analysis
Maintainer FreedomIntelligence · Last updated April 1, 2026
Analyze protein-protein interaction networks using STRING, BioGRID, and SASBDB databases. Maps protein identifiers, retrieves interaction networks with confidence scores, performs functional enrichment analysis (GO/KEGG/Reactome), and optionally includes structural data. No API key required for core functionality (STRING). Use when analyzing protein networks, discovering interaction partners, identifying functional….
Original source
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/tooluniverse-protein-interactions
- Maintainer
- FreedomIntelligence
- License
- MIT
- Last updated
- April 1, 2026
Skill Snapshot
Key Details From SKILL.md
Key Notes
- Comprehensive protein interaction network analysis using ToolUniverse tools. Analyzes protein networks through a 4-phase workflow: identifier mapping, network retrieval, enrichment analysis, and optional structural data.
- result = analyze_protein_network( tu=tu, proteins=["TP53", "MDM2", "ATM", "CHEK2"], species=9606, # Human confidence_score=0.7 # High confidence ).
Source Doc
Excerpt From SKILL.md
Features
✅ Identifier Mapping - Convert protein names to database IDs (STRING, UniProt, Ensembl) ✅ Network Retrieval - Get interaction networks with confidence scores (0-1.0) ✅ Functional Enrichment - GO terms, KEGG pathways, Reactome pathways ✅ PPI Enrichment - Test if proteins form functional modules ✅ Structural Data - Optional SAXS/SANS solution structures (SASBDB) ✅ Fallback Strategy - STRING primary (no API key) → BioGRID secondary (if key available)
Databases Used
| Database | Coverage | API Key | Purpose |
|---|---|---|---|
| STRING | 14M+ proteins, 5,000+ organisms | ❌ Not required | Primary interaction source |
| BioGRID | 2.3M+ interactions, 80+ organisms | ✅ Required | Fallback, curated data |
| SASBDB | 2,000+ SAXS/SANS entries | ❌ Not required | Solution structures |
Basic Usage
from tooluniverse import ToolUniverse
from python_implementation import analyze_protein_network
Use cases
- Use when analyzing protein networks, discovering interaction partners, identifying functional modules, or studying protein complexes.
Not for
- Do not rely on this catalog entry alone for installation or maintenance details.
Related skills
Related skills
AL
Data & Repro
alphafold
Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) P…
FreedomIntelligence/OpenClaw-Medical-SkillsView
AL
Data & Repro
AlphaFold DB
AlphaFold DB is a public repository of AI-predicted 3D protein structures for over 200 million proteins, maintained by DeepMind and EMBL-EBI…
K-Dense-AI/claude-scientific-skillsView
AN
Data & Repro
antibody-design-agent
Antibody design: epitope mapping, CDR engineering, bispecific construction.
FreedomIntelligence/OpenClaw-Medical-SkillsView