PackageBioinformaticsScientific Packages

pysam

Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.

This page mirrors an upstream repository entry. It does not mean the skill is already part of the SCI Skills curated catalog.

Raw path
scientific-skills/pysam
Allowed tools
-
Repository version
2.31.0
Synced at
March 27, 2026

About this skill

About this skill

Pysam is a Python module for reading, manipulating, and writing genomic datasets. Read/write SAM/BAM/CRAM alignment files, VCF/BCF variant files, and FASTA/FASTQ sequences with a Pythonic interface to htslib. Query tabix-indexed files, perform pileup analysis for coverage, and execute samtools/bcftools commands.

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