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数据与复现
BI
bio-genome-assembly-scaffolding
维护者 FreedomIntelligence · 最近更新 2026年4月1日
Scaffold contigs with Hi-C, optical mapping, or long reads.
原始来源
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-genome-assembly-scaffolding
- 维护者
- FreedomIntelligence
- 许可
- MIT
- 最近更新
- 2026年4月1日
技能摘要
来自 SKILL.md 的关键信息
核心说明
- bwa index draft_assembly.fa bwa mem -5SP -t 16 draft_assembly.fa hic_R1.fq.gz hic_R2.fq.gz | \ samtools view -@ 8 -bhS - > aligned.bam。
原始文档
SKILL.md 摘录
Convert BAM to BED
bedtools bamtobed -i aligned.bam | sort -k4 > aligned.bed
Run YaHS
yahs draft_assembly.fa aligned.bed -o scaffolds
Run with error correction
yahs draft_assembly.fa aligned.bed -o scaffolds --no-contig-ec
适用场景
- Use bio-genome-assembly-scaffolding ，用于 genomics 、 bioinformatics workflows。
- Apply bio-genome-assembly-scaffolding to sequencing，variant，或 omics analysis tasks。
不适用场景
- Do not rely on this catalog entry alone ，用于 installation 或 maintenance details。
上游相关技能
- genome-assembly/long-read-assembly - Generate initial contigs
- genome-assembly/assembly-polishing - Polish before scaffolding
- genome-assembly/assembly-qc - Validate final assembly
- hi-c-analysis/hic-data-io - Hi-C data processing
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