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数据与复现
BI
bio-read-alignment-bowtie2-alignment
维护者 FreedomIntelligence · 最近更新 2026年4月1日
Align short reads with Bowtie2; local and end-to-end modes.
原始来源
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-read-alignment-bowtie2-alignment
- 维护者
- FreedomIntelligence
- 许可
- MIT
- 最近更新
- 2026年4月1日
技能摘要
来自 SKILL.md 的关键信息
核心说明
- bowtie2-build reference.fa reference_index。
- bowtie2-build --threads 8 reference.fa reference_index。
原始文档
SKILL.md 摘录
Paired-end reads
bowtie2 -p 8 -x reference_index -1 reads_1.fq.gz -2 reads_2.fq.gz -S aligned.sam
Single-end reads
bowtie2 -p 8 -x reference_index -U reads.fq.gz -S aligned.sam
Direct to sorted BAM
bowtie2 -p 8 -x reference_index -1 r1.fq.gz -2 r2.fq.gz |
samtools sort -@ 4 -o aligned.sorted.bam -
适用场景
- Use bio-read-alignment-bowtie2-alignment ，用于 genomics 、 bioinformatics workflows。
- Apply bio-read-alignment-bowtie2-alignment to sequencing，variant，或 omics analysis tasks。
不适用场景
- Do not rely on this catalog entry alone ，用于 installation 或 maintenance details。
上游相关技能
- read-qc/fastp-workflow - Preprocess reads before alignment
- alignment-files/alignment-sorting - Post-alignment processing
- chip-seq/peak-calling - ChIP-seq analysis
- atac-seq/atac-peak-calling - ATAC-seq analysis
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