数据与复现生物信息与基因组学FreedomIntelligence/OpenClaw-Medical-Skills数据与复现
BI

bio-sequence-properties

维护者 FreedomIntelligence · 最近更新 2026年4月1日

Compute sequence properties: MW, pI, hydrophobicity, extinction coefficient.

OpenClawNanoClaw分析处理复现实验bio-sequence-properties🧠 bioos extended suitebioos extended bioinformatics suitecompute

原始来源

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-sequence-properties

维护者
FreedomIntelligence
许可
MIT
最近更新
2026年4月1日

技能摘要

来自 SKILL.md 的关键信息

2 min

核心说明

  • Calculate physical 、 chemical properties of biological sequences ,使用 Biopython。
  • mw_ds = molecular_weight(dna,double_stranded=True)。

原始文档

SKILL.md 摘录

GC at Codon Positions (GC123)

Analyze GC content at each codon position (useful for codon bias analysis):

from Bio.SeqUtils import GC123

seq = Seq('ATGCGATCGATCGATCGATCG')
gc_total, gc_pos1, gc_pos2, gc_pos3 = GC123(seq)

## GC Skew

Calculate (G-C)/(G+C) in sliding windows to identify replication origins:

## Molecular Weight

```python
from Bio.SeqUtils import molecular_weight

dna = Seq('ATGCGATCG')
mw = molecular_weight(dna)  # Single-stranded DNA weight

适用场景

  • Use bio-sequence-properties ,用于 genomics 、 bioinformatics workflows。
  • Apply bio-sequence-properties to sequencing,variant,或 omics analysis tasks。

不适用场景

  • Do not rely on this catalog entry alone ,用于 installation 或 maintenance details。

上游相关技能

  • seq-objects - Create Seq objects for property calculation
  • sequence-io/sequence-statistics - File-level statistics (N50, totals)
  • codon-usage - GC123 for codon position analysis
  • transcription-translation - Translate before protein analysis
  • alignment-files/bam-statistics - samtools stats for alignment-level GC and quality stats

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