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bone-marrow-ai-agent
维护者 FreedomIntelligence · 最近更新 2026年4月1日
Bone marrow analysis: blast counting, immunophenotyping, disease classification.
原始来源
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bone-marrow-ai-agent
- 维护者
- FreedomIntelligence
- 许可
- MIT
- 最近更新
- 2026年4月1日
技能摘要
来自 SKILL.md 的关键信息
核心说明
- Bone Marrow AI Agent provides comprehensive AI-driven analysis of bone marrow aspirate 、 biopsy specimens. It performs automated cell identification,differential counting,morphological assessment,、 pattern recognition ,用于 hematologic disease diagnosis。
- When performing automated bone marrow differential counts ,面向 aspirate smears。
- To identify morphological abnormalities (dysplasia,blasts,abnormal cells)。
- 用于 pattern recognition in myelodysplastic syndromes (MDS),leukemias,、 other disorders。
- When assessing cellularity,fibrosis,、 infiltration in trephine biopsies。
原始文档
SKILL.md 摘录
Core Capabilities
-
Cell Classification: Deep learning identification and classification of 15+ bone marrow cell types with >95% accuracy.
-
Automated Differential: Rapid 500-cell differential counts from digital aspirate images.
-
Dysplasia Detection: AI recognition of dyserythropoiesis, dysgranulopoiesis, and dysmegakaryopoiesis.
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Blast Quantification: Accurate blast percentage enumeration for AML/MDS classification.
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Biopsy Analysis: Cellularity estimation, fibrosis grading, and infiltration pattern recognition.
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Quality Assessment: Automated specimen adequacy and hemodilution detection.
Cell Types Classified
| Lineage | Cell Types | Key Features |
|---|---|---|
| Erythroid | Pronormoblast, basophilic, polychromatic, orthochromatic | Size, chromatin, cytoplasm color |
| Myeloid | Myeloblast, promyelocyte, myelocyte, metamyelocyte, band, seg | Granules, nuclear shape |
| Monocytic | Monoblast, promonocyte, monocyte | Nuclear folding, cytoplasm |
| Lymphoid | Lymphocyte, plasma cell | Size, chromatin density |
| Megakaryocytic | Megakaryocytes (all stages) | Size, nuclear lobation |
| Other | Mast cells, osteoblasts, osteoclasts | Distinctive morphology |
Workflow
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Input: Bone marrow aspirate images (Wright-Giemsa stained) or biopsy sections (H&E).
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Preprocessing: Color normalization, focus stacking, region of interest selection.
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Cell Detection: Instance segmentation to identify individual cells.
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Classification: CNN/CoAtNet model assigns cell type labels.
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Differential: Aggregate counts and calculate percentages.
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Pattern Recognition: Identify disease-associated morphological patterns.
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Output: Differential count, morphology report, diagnostic suggestions.
适用场景
- When performing automated bone marrow differential counts ,面向 aspirate smears。
- To identify morphological abnormalities (dysplasia,blasts,abnormal cells)。
- 用于 pattern recognition in myelodysplastic syndromes (MDS),leukemias,、 other disorders。
- When assessing cellularity,fibrosis,、 infiltration in trephine biopsies。
不适用场景
- Do not rely on this catalog entry alone ,用于 installation 或 maintenance details。
上游相关技能
- Flow_Cytometry_AI - For immunophenotyping correlation
- AML_Classification - For WHO/ICC AML subtyping
- MDS_Diagnosis - For MDS-specific analysis
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