数据与复现临床医学与医药FreedomIntelligence/OpenClaw-Medical-Skills数据与复现
BO

bone-marrow-ai-agent

维护者 FreedomIntelligence · 最近更新 2026年4月1日

Bone marrow analysis: blast counting, immunophenotyping, disease classification.

OpenClawNanoClaw分析处理复现实验bone-marrow-ai-agent🧠 bioos extended suitehematology & blood disordersbone

原始来源

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bone-marrow-ai-agent

维护者
FreedomIntelligence
许可
MIT
最近更新
2026年4月1日

技能摘要

来自 SKILL.md 的关键信息

2 min

核心说明

  • Bone Marrow AI Agent provides comprehensive AI-driven analysis of bone marrow aspirate 、 biopsy specimens. It performs automated cell identification,differential counting,morphological assessment,、 pattern recognition ,用于 hematologic disease diagnosis。
  • When performing automated bone marrow differential counts ,面向 aspirate smears。
  • To identify morphological abnormalities (dysplasia,blasts,abnormal cells)。
  • 用于 pattern recognition in myelodysplastic syndromes (MDS),leukemias,、 other disorders。
  • When assessing cellularity,fibrosis,、 infiltration in trephine biopsies。

原始文档

SKILL.md 摘录

Core Capabilities

  1. Cell Classification: Deep learning identification and classification of 15+ bone marrow cell types with >95% accuracy.

  2. Automated Differential: Rapid 500-cell differential counts from digital aspirate images.

  3. Dysplasia Detection: AI recognition of dyserythropoiesis, dysgranulopoiesis, and dysmegakaryopoiesis.

  4. Blast Quantification: Accurate blast percentage enumeration for AML/MDS classification.

  5. Biopsy Analysis: Cellularity estimation, fibrosis grading, and infiltration pattern recognition.

  6. Quality Assessment: Automated specimen adequacy and hemodilution detection.

Cell Types Classified

LineageCell TypesKey Features
ErythroidPronormoblast, basophilic, polychromatic, orthochromaticSize, chromatin, cytoplasm color
MyeloidMyeloblast, promyelocyte, myelocyte, metamyelocyte, band, segGranules, nuclear shape
MonocyticMonoblast, promonocyte, monocyteNuclear folding, cytoplasm
LymphoidLymphocyte, plasma cellSize, chromatin density
MegakaryocyticMegakaryocytes (all stages)Size, nuclear lobation
OtherMast cells, osteoblasts, osteoclastsDistinctive morphology

Workflow

  1. Input: Bone marrow aspirate images (Wright-Giemsa stained) or biopsy sections (H&E).

  2. Preprocessing: Color normalization, focus stacking, region of interest selection.

  3. Cell Detection: Instance segmentation to identify individual cells.

  4. Classification: CNN/CoAtNet model assigns cell type labels.

  5. Differential: Aggregate counts and calculate percentages.

  6. Pattern Recognition: Identify disease-associated morphological patterns.

  7. Output: Differential count, morphology report, diagnostic suggestions.

适用场景

  • When performing automated bone marrow differential counts ,面向 aspirate smears。
  • To identify morphological abnormalities (dysplasia,blasts,abnormal cells)。
  • 用于 pattern recognition in myelodysplastic syndromes (MDS),leukemias,、 other disorders。
  • When assessing cellularity,fibrosis,、 infiltration in trephine biopsies。

不适用场景

  • Do not rely on this catalog entry alone ,用于 installation 或 maintenance details。

上游相关技能

  • Flow_Cytometry_AI - For immunophenotyping correlation
  • AML_Classification - For WHO/ICC AML subtyping
  • MDS_Diagnosis - For MDS-specific analysis

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