bulk-rna-seq-batch-correction-with-combat

核心说明

• Apply this skill when user has multiple bulk expression matrices measured across different batches 、 needs to harmonise them before downstream analysis. It follows t_bulk_combat.ipynb，w hich demonstrates pyComBat workflow on ovarian cancer microarray cohorts。
• Load omicverse as ov，anndata，pandas as pd，、 matplotlib.pyplot as plt。
• Call ov.ov_plot_set() (aliased ov.plot_set() in some releases) to align figures ，支持 omicverse styling。
• Read prepared pickled matrices (或 user-provided expression tables) ，支持 pd.read_pickle(...)/pd.read_csv(...)。
• Transpose to gene × sample before wrapping them in anndata.AnnData objects so adata.obs stores sample metadata。