AN
数据与复现
AnnData
AnnData is a Python package for handling annotated data matrices, storing experimental measurements (X) alongside observ…
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数据与复现
SC
scrna-qc
维护者 FreedomIntelligence · 最近更新 2026年4月1日
Single-cell RNA-seq quality control: doublet removal, ambient RNA, filtering thresholds.
原始来源
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/scrna-qc
- 维护者
- FreedomIntelligence
- 许可
- MIT
- 最近更新
- 2026年4月1日
技能摘要
来自 SKILL.md 的关键信息
核心说明
- description (10-20 chars)：QC autopilot。
- keywords：scRNAseq，MAD，h5ad，QC，plots。
- description (10-20 chars)：QC autopilot keywords：scRNAseq，MAD，h5ad，QC，plots。
- 1. Accept.h5ad，10x.h5，或 10x directory inputs；set mitochondrial/ribosomal patterns as needed. 2. Run qc_analysis.py (CLI) 或 call qc_core helpers to compute metrics，apply MAD thresholds，、 filter cells/genes. 3. Generate standard plots (metrics before/after，threshold overlays) plus filtered data artifacts. 4. Document parameters (mad_counts/genes/mt，mt_threshold，min_cells，log1p flag) inside summary JSON. 5. Provide guidance on next steps (doublet detection，downstream analysis)。
原始文档
SKILL.md 摘录
Guardrails
- Adjust MT% expectations for tissue context; avoid over-filtering rare populations.
- This workflow is QC only—doublet handling and batch correction stay separate.
- Keep reproducibility by storing command invocations and environment info.
适用场景
- Use scrna-qc ，用于 single-cell 或 spatial omics analysis。
- Apply scrna-qc to 聚类，integration，或 trajectory workflows。
不适用场景
- Do not rely on this catalog entry alone ，用于 installation 或 maintenance details。
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