数据与复现单细胞与空间组学FreedomIntelligence/OpenClaw-Medical-Skills数据与复现
SI

single2spatial-spatial-mapping

维护者 FreedomIntelligence · 最近更新 2026年4月1日

Apply this skill when converting single-cell references into spatially resolved profiles. It follows [`t_single2spatial.ipynb`](../../omicverse_guide/docs/Tutorials-bulk2single/t_single2spatial.ipynb), demonstrating how Single2Spatial trains on PDAC scRNA-seq and Visium data, reconstructs spot-level proportions, and visualises marker expression.

OpenClawNanoClaw分析处理复现实验single-to-spatial-mapping🔬 omics & computational biologysingle-cell & spatial omicsmap

原始来源

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/single-to-spatial-mapping

维护者
FreedomIntelligence
许可
MIT
最近更新
2026年4月1日

技能摘要

来自 SKILL.md 的关键信息

2 min

核心说明

  • Apply this skill when converting single-cell references into spatially resolved profiles. It follows t_single2spatial.ipynb,demonstrating how Single2Spatial trains on PDAC scRNA-seq 、 Visium data,reconstructs spot-level proportions,、 visualises marker expression。
  • Load omicverse as ov,scanpy as sc,anndata,pandas as pd,numpy as np,、 matplotlib.pyplot as plt。
  • Call ov.utils.ov_plot_set() (或 ov.plot_set() in older versions) to align plots ,支持 omicverse styling。
  • Read processed matrices ,支持 pd.read_csv(...) then create AnnData objects (anndata.AnnData(raw_df.T))。
  • Attach metadata:single_data.obs = pd.read_csv(...)[['Cell_type']] 、 spatial_data.obs = pd.read_csv(... ) containing coordinates 、 slide metadata。

原始文档

SKILL.md 摘录

Examples

  • "Train Single2Spatial on PDAC scRNA-seq and Visium slides, then visualise REG1A and CLDN1 spatial expression."
  • "Load a saved Single2Spatial checkpoint to regenerate spot-level cell-type proportions for reporting."
  • "Plot reconstructed cell-type maps with omicverse palettes to compare against histology."

适用场景

  • Use single2spatial-spatial-mapping ,用于 single-cell 或 spatial omics analysis。
  • Apply single2spatial-spatial-mapping to 聚类,integration,或 trajectory workflows。

不适用场景

  • Do not rely on this catalog entry alone ,用于 installation 或 maintenance details。

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