流程自动化科研基础设施FreedomIntelligence/OpenClaw-Medical-Skills数据与复现
SP

SpatialAgent

维护者 FreedomIntelligence · 最近更新 2026年4月1日

SpatialAgent。

OpenClawNanoClaw分析处理复现实验spatialagentopenclaw medical skillsadditional scientific toolsspatialagent

原始来源

FreedomIntelligence/OpenClaw-Medical-Skills

https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/SpatialAgent

维护者
FreedomIntelligence
许可
MIT
最近更新
2026年4月1日

技能摘要

来自 SKILL.md 的关键信息

2 min

核心说明

  • SpatialAgent focuses on biological interpretation of spatial transcriptomics data,specifically aiming to propose mechanistic hypotheses about tissue organization 、 cellular interactions。
  • Mechanistic Interpretation:When you have clusters 或 spatial domains 、 need to understand why they are organized that way。
  • Cell-Cell Interaction:To predict 、 interpret ligand-receptor interactions in spatial context。
  • Hypothesis Generation:To propose biological mechanisms driving observed spatial heterogeneity。
  • Mechanistic Interpretation:When you have clusters 或 spatial domains 、 need to understand why they are organized that way. Cell-Cell Interaction:To predict 、 interpret ligand-receptor interactions in spatial context. * Hypothesis Generation:To propose biological mechanisms driving observed spatial heterogeneity。

原始文档

SKILL.md 摘录

Core Capabilities

  1. Tissue Organization Analysis: Decodes the structural logic of tissues (e.g., layers, niches).
  2. Cellular Interaction Prediction: Identifies potential signaling pathways active at domain boundaries.
  3. Hypothesis Proposal: Generates testable biological hypotheses based on spatial data.

Workflow

  1. Input Analysis: Accepts processed ST data (e.g., cluster annotations, DEG lists per spatial domain).
  2. Knowledge Retrieval: Queries biological knowledge bases regarding the observed cell types and genes.
  3. Synthesis: Constructs a narrative explaining the spatial arrangement (e.g., "The proximity of fibroblasts and tumor cells suggests a desmoplastic reaction mediated by TGF-beta signaling...").

Example Usage

User: "Why are the macrophages located at the boundary of the tumor core in this sample?"

Agent Action:

  1. Analyzes the gene expression of macrophages and adjacent tumor cells.
  2. Checks for ligand-receptor pairs (e.g., CSF1-CSF1R).
  3. Proposes: "Macrophages are likely recruited by CSF1 secreted by the tumor cells, forming an immunosuppressive barrier..."

适用场景

  • **Mechanistic Interpretation**:When you have clusters 或 spatial domains 、 need to understand *why* they are organi。

不适用场景

  • Do not rely on this catalog entry alone ,用于 installation 或 maintenance details。

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