AA
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数据与复现
TO
tooluniverse-pharmacovigilance
维护者 FreedomIntelligence · 最近更新 2026年4月1日
Analyze drug safety signals from FDA adverse event reports, label warnings, and pharmacogenomic data. Calculates disproportionality measures (PRR, ROR), identifies serious adverse events, assesses pharmacogenomic risk variants. Use when asked about drug safety, adverse events, post-market surveillance, or risk-benefit assessment.
原始来源
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/tooluniverse-pharmacovigilance
- 维护者
- FreedomIntelligence
- 许可
- MIT
- 最近更新
- 2026年4月1日
技能摘要
来自 SKILL.md 的关键信息
核心说明
- Systematic drug safety analysis ，使用 FAERS adverse event data，FDA labeling，PharmGKB pharmacogenomics，、 clinical trial safety signals。
- KEY PRINCIPLES：1. Report-first approach - Create report file FIRST，update progressively 2. Signal quantification - Use disproportionality measures (PRR，ROR) 3. Severity stratification - Prioritize serious/fatal events 4. Multi-source triangulation - FAERS，labels，trials，literature 5. Pharmacogenomic context - Include genetic risk factors 6. Actionable output - Risk-benefit summary ，支持 recommendations 7. English-first queries - Always use English drug names 、 search terms in tool calls，even if user writes in another language. Only try original-language terms as fallback. Respond in user's language。
原始文档
SKILL.md 摘录
When to Use
Apply when user asks:
- "What are the safety concerns for [drug]?"
- "What adverse events are associated with [drug]?"
- "Is [drug] safe? What are the risks?"
- "Should I be concerned about [specific adverse event] with [drug]?"
- "Compare safety profiles of [drug A] vs [drug B]"
- "Pharmacovigilance analysis for [drug]"
1. Report-First Approach (MANDATORY)
-
Create the report file FIRST:
- File name:
[DRUG]_safety_report.md - Initialize with all section headers
- Add placeholder text:
[Researching...]
- File name:
-
Progressively update as you gather data
-
Output separate data files:
[DRUG]_adverse_events.csv- Ranked AEs with counts/signals[DRUG]_pharmacogenomics.csv- PGx variants and recommendations
2. Citation Requirements (MANDATORY)
Every safety signal MUST include source:
适用场景
- 适合在asked about drug safety，adverse events，post-market surveillance，或 risk-benefit assessment时使用。
不适用场景
- Do not rely on this catalog entry alone ，用于 installation 或 maintenance details。
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