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数据与复现
TO
tooluniverse-target-research
维护者 FreedomIntelligence · 最近更新 2026年4月1日
Gather comprehensive biological target intelligence from 9 parallel research paths covering protein info, structure, interactions, pathways, expression, variants, drug interactions, and literature. Features collision-aware searches, evidence grading (T1-T4), explicit Open Targets coverage, and mandatory completeness auditing. Use when users ask about drug targets, proteins, genes, or need target validation, druggabi….
原始来源
FreedomIntelligence/OpenClaw-Medical-Skills
https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/tooluniverse-target-research
- 维护者
- FreedomIntelligence
- 许可
- MIT
- 最近更新
- 2026年4月1日
技能摘要
来自 SKILL.md 的关键信息
核心说明
- Gather complete target intelligence by exploring 9 parallel research paths. Supports targets identified by gene symbol，UniProt accession，Ensembl ID，或 gene name。
- KEY PRINCIPLES：1. Report-first approach - Create report file FIRST，then populate progressively 2. Tool parameter verification - Verify params ，通过 get_tool_info before calling unfamiliar tools 3. Evidence grading - Grade all claims by evidence strength (T1-T4) 4. Citation requirements - Every fact must have inline source attribution 5. Mandatory completeness - All sections must exist ，支持 data minimums 或 explicit "No data" notes 6. Disambiguation first - Resolve all identifiers before research 7. Negative results documented - "No drugs found" is data；empty sections are failures 8. Collision-aware literature search - Detect 、 filter naming collisions 9. English-first queries - Always use English terms in tool calls，even if user writes in another language. Translate gene names，disease names，、 search terms to English. Only try original-language terms as fallback if English returns no results. Respond in user's language。
- tool_info = tu.tools.get_tool_info(tool_name="Reactome_map_uniprot_to_pathways")。
原始文档
SKILL.md 摘录
Phase 0: Tool Parameter Verification (CRITICAL)
BEFORE calling ANY tool for the first time, verify its parameters:
## Known Parameter Corrections (Updated)
| Tool | WRONG Parameter | CORRECT Parameter |
|------|-----------------|-------------------|
| `Reactome_map_uniprot_to_pathways` | `uniprot_id` | `id` |
| `ensembl_get_xrefs` | `gene_id` | `id` |
| `GTEx_get_median_gene_expression` | `gencode_id` only | `gencode_id` + `operation="median"` |
| `OpenTargets_*` | `ensemblID` | `ensemblId` (camelCase) |
## GTEx Versioned ID Fallback (CRITICAL)
GTEx often requires versioned Ensembl IDs. If `ENSG00000123456` returns empty:
```python
适用场景
- Ask about drug target，protein，或 gene。
- Need target validation 或 assessment。
- Request druggability analysis。
- Want comprehensive target profiling。
不适用场景
- Do not rely on this catalog entry alone ，用于 installation 或 maintenance details。
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